The treatment of type 2 diabetes has evolved over the past decade, and incretin-based drugs, including dipeptidyl peptidase 4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1)
Magen und Dünndarm
Magen und Dünndarm
Do DPP4 Inhibitors and GLP-1 Receptor Agonists Increase the Risk of Intestinal Obstruction?
Does Low-Dose Aspirin Result in Anemia in Older Patients?
Daily intake of low-dose aspirin increases the risk of major bleeding, but its effect on iron deficiency and anemia is less studied. This study, a
Is Digital Gut-Directed Hypnotherapy Better Than Muscle Relaxation in Patients With Irritable Bowel Syndrome?
In addition to dietary modification and pharmacologic therapy, behavioral therapy has become a recognized treatment for irritable bowel syndrome (IBS) and is now integrated into
Malignant Tumor Bleeding: Is Hemostatic Powder Superior to Standard Endoscopy?
Treating bleeding malignant tumors is challenging because they tend to be diffusely friable. Hemostatic powder is a relatively new tool in the endoscopic armamentarium for
Band and Biopsy: An Easier Way to Sample and Remove Small Subepithelial Lesions?
Diagnosis and resection of subcentimeter subepithelial tumors (SETs) can be challenging. One problem with endoscopic band ligation (EBL) and allowing the lesion to slough is
Does Eradication of Helicobacter pylori Lower the Chance of Gastric Cancer?
Helicobacter pylori eradication has been shown to decrease the risk of noncardia gastric adenocarcinoma (NCGA) in Asia; however, the data in the United States are limited.
Can We Improve Quality in ERCP and EUS?
ERCP and EUS are essential in treating a variety of disease entities. Metrics exist to measure performance quality, but data are necessary to improve quality
Just Because Something Is New, Does It Mean It Works?
The development of hemostatic powders has increased the tools in our armamentarium to treat GI bleeding. However, data on their utility in peptic ulcer bleeding
Is Motorized Spiral Enteroscopy All That It Is Cut Out To Be?
In 2016, motorized spiral enteroscopy (mSe) was introduced to facilitate visualization for diagnosis and therapy of the small bowel. The primary aim of this review
Is Cold Snare Resection a Good Idea for Duodenal Adenomas?
Resection of duodenal adenomas (DAs) can be challenging, in part due to the thinness of the duodenal wall and its vascularity. Both postprocedural bleeding (PPB)
Could Upper GI Eosinophilia Account for Abdominal Pain?
Eosinophilic gastrointestinal diseases (EGIDs) are rare inflammatory conditions of the GI tract characterized by tissue eosinophilia and chronic GI symptoms. EGIDs include eosinophilic gastritis (EoG)
Is There an Increased Risk of Proximal Gastrointestinal Cancer After a Positive Fecal Immunochemical Test?
The fecal immunochemical test (FIT) is a simple, noninvasive, at-home study that detects blood in the stool and is used for colon cancer (CRC) screening
Is Juvenile Polyposis Syndrome Associated With a Significant Risk of Gastric Cancer?
Juvenile polyposis syndrome (JPS), in which patients develop juvenile polyps, is uncommon but is thought to be associated with an increased risk of gastrointestinal cancers.
Refractory Celiac Disease: What to Do
Refractory celiac disease (RCD) is defined as celiac disease with persistent symptoms despite at least 12 months of a strict gluten-free diet. There are 2
Are Over-the-Scope Clips Superior to Other Methods of Hemostasis?
Nonvariceal upper gastrointestinal bleeding (NVUGIB) is potentially life-threatening and a common cause of hospitalization. Endoscopy is the procedure of choice for the evaluation and management
Are Proton Pump Inhibitors Truly Dangerous?
The use of proton pump inhibitors (PPIs) has continually increased over the past 20 to 30 years. As a result, interest has grown in the
How Often Do Patients With Dyspepsia Have Pathology on Endoscopy?
Dyspepsia is a worldwide disease that interferes with quality of life. A 2010 systematic review investigated the prevalence of endoscopic findings in patients with dyspepsia;
What Are the Risk Factors for Abdominal Pain Disorders of Gut-Brain Interaction?
Abdominal pain-related disorders of gut-brain interaction (AP-DGBI) affect a sizable portion of the population. Irritable bowel syndrome (IBS) is one of the most common forms
Does Eradication of Helicobacter pylori Really Decrease Gastric Cancer Incidence and Mortality?
Gastric cancer is the third most common cause of cancer-related death in the world. Through the intestinal metaplasia pathway, Helicobacter pylori is a class 1 carcinogen and
Utility of Motorized Spiral Enteroscopy
Motorized spiral enteroscopy (MSE) is innovative technology designed to facilitate advancement of the enteroscope across the small bowel. Preliminary studies have shown MSE to be
What Are the Long-Term Outcomes of Gastric Peroral Endoscopic Myotomy Performed for Gastroparesis?
Refractory gastroparesis (RG) negatively impacts the quality of life, and treatments to date have worked variably. Gastric peroral endoscopic myotomy (G-POEM), first performed in 2013,
When Proton Pump Inhibitors Should Be Discontinued: American Gastroenterological Association Clinical Practice Update
Proton pump inhibitors (PPIs) are prescribed for various indications, sometimes with clear evidence-based benefit and sometimes with little to no proven benefit. The purpose of
Does a Low FODMAP Diet Help Patients With Celiac Disease?
The incidence of celiac disease has been increasing over time and is commonly encountered in GI practice. Although a gluten-free diet leads to pathologic disease
Is Cold Snare Piecemeal EMR Adequate in Treating Duodenal Adenomas?
Traditionally, nonampullary small-bowel adenomas ≥10 mm in diameter are resected utilizing cautery. Unfortunately, since the small bowel is thin-walled and highly vascular, adverse events are
Endoscopic Submucosal Dissection Enough to Cure Early Gastric Cancer?
Over the past decade, with advances in endoscopic resection (ER) techniques, there has been a trend toward removing early gastric cancer (EGC) with ER, especially
How Best to Treat Collagenous Gastritis?
Collagenous gastritis (CG) is an uncommon disorder characterized by subepithelial collagen deposition in the stomach. Symptoms vary depending on the phenotype (pediatric-onset vs adult-onset). Treatment
Key to Optimal Pathology Reporting for Endoscopic Gastric Cancer Resection Specimens
Endoscopic resection (ER) of early gastric neoplasia is being performed with increasing frequency by endoscopists. Complete and accurate reporting of pathology is imperative to provide
Refractory Gastroparesis: Expert Recommendations
Gastroparesis is a vexing problem and often has overlapping symptoms with functional dyspepsia. In this update from the American Gastroenterological Association, medically refractory gastroparesis is
Does Hemostatic Powder Lessen Bleeding After Endoscopic Submucosal Dissection?
Bleeding after endoscopic submucosal dissection (ESD) is one of the most common adverse events, but the risk of post-ESD bleeding varies, depending on antiplatelet or
Diagnosis and Management of Atrophic Gastritis: Clinical Practice Update From the American Gastroenterological Association
Patients with atrophic gastritis (AG) are at increased risk for gastric cancer; however, the diagnosis and surveillance of AG are not well-defined. Algorithms for the
PEG Placement: Is the Radiologic, Surgical, or Endoscopic Technique Safest?
The optimal technique for gastrostomy tube placement remains undefined. This retrospective study used the Nationwide Readmissions Database and the International Classification of Diseases Procedure Coding
Removing Duodenal Epithelial Lesions: Does Underwater Endoscopic Resection Work?
Underwater endoscopic mucosal resection (UEMR) has been increasingly utilized in the resection of colonic and duodenal mucosal lesions. Its use for resection of nonpolypoid superficial
Endoscopic Management of Perforations: AGA Clinical Practice Update
A practice update from the American Gastroenterological Association used expert review and focus on methodologies to develop best practice recommendations for the management of endoscopic
Do Individuals With Celiac Disease Really Have an Increased Risk of Cancer?
Diagnosis of celiac disease has increased significantly over the past decade. The risk of cancer in this patient population is thought to be increased, although
Does Ranitidine Use Increase Risk of Bladder Cancer?
In 2020, the U.S. Food and Drug Administration and other similar bodies recalled all ranitidine products, secondary to a possible increased association with several types
Is There a Method to Improve Examination of the Small Bowel With Capsule Endoscopy?
The ability of video capsule endoscopy (VCE) to detect small-bowel (SB) pathology is dependent on adequate visibility and motility. This single-center, prospective, randomized, controlled trial
Pancreatic Cystic Lesions: Is Fluid Glucose Better Than Carcinoembryonic Antigen?
Differentiating pancreatic mucinous from nonmucinous cysts can be challenging, and the pancreatic cyst fluid (PCF) carcinoembryonic antigen (CEA) level has suboptimal accuracy. Adjunct tests, such
Management of Bariatric Complications: An American Gastroenterological Association Clinical Practice Update
More than 200,000 bariatric surgeries took place in 2018. Of these, 95% were either a sleeve gastrectomy or Roux-En-Y gastric bypass. Although the 90-day mortality
Is Gastroparesis Truly Different From Functional Dyspepsia?
Patients with functional dyspepsia (FD) and gastroparesis are commonly seen, diagnosed, and treated in gastroenterology clinics. Though we think of these diseases as two separate
Are Proton Pump Inhibitors Associated With Increased Mortality?
There has been significant media attention on the risks of proton pump inhibitors (PPIs) noted in observational studies, including associated risks of pneumonia, Clostridium difficile,
Does Ranitidine Use Increase Cancer Risk?
Ranitidine is a widely used H2-receptor antagonist used to treat reflux and peptic ulcer disease. Recently, the U.S. Food and Drug Association (FDA) discontinued sales
Can We Decrease Lesion Recurrence After Duodenal Endoscopic Mucosal Resection?
Laterally spreading lesions (LSLs) of the duodenum are increasingly being diagnosed and treated endoscopically. Although endoscopic resection of the thin and vascular duodenal wall is
Resumption of Anticoagulation After GI Bleeding: Is It a Good Idea?
Millions of individuals with atrial fibrillation are prescribed anticoagulants (warfarin or direct oral anticoagulants [DOACs]) to decrease the incidence of thromboembolic events. In a subset
Endoscopic Management of Gastroduodenal Obstruction
Gastric outlet obstruction (GOO) can result in significant morbidity. Symptoms include early satiety, nausea, vomiting, and abdominal pain, which are frequently associated with weight loss.
Is Gastric Electric Stimulation Cost-Effective in Patients With Refractory Vomiting?
Medication-refractory nausea and vomiting, which is often due to gastric dysmotility, is a challenging problem. High-frequency gastric electrical stimulation (GES), which was approved by the
Should We Be Treating Postsurgical Leaks Endoscopically?
Postoperative leaks are difficult to treat; however, the evolution of therapeutic endoscopy has allowed less-invasive repair techniques in an attempt to avoid repeat surgery. This
How Safe Is Endoscopic Gastrostomy Tube Placement?
The invasive nature of the endoscopic placement of a gastrostomy tube is associated with higher morbidity and mortality compared to other routine endoscopic procedures. Alternative
Is Endoscopic Sleeve Gastroplasty the Solution?
The prevalence of obesity in the United States has reached an epidemic level and is associated with conditions such as insulin resistance (IR) and nonalcoholic
Should Asian Americans Be Routinely Screened for Gastric Cancer With Endoscopy?
There are no current guidelines in the United States for gastric cancer screening, even with a high population of immigrants from Asian-Pacific countries. Studies have
Hope for Those Suffering From Gastroparesis?
Gastroparesis is a chronic medical condition that can cause unpleasant and refractory symptoms that adversely affect quality of life. Unfortunately, metoclopramide, which can cause serious
Endoscopic Submucosal Dissection Outcomes for Early Gastric Lesions in North America
There are sufficient data in Asia to demonstrate that endoscopic submucosal dissection (ESD) has equivalent outcomes to surgical intervention for early gastric cancer (EGC). Moreover,
Familial Adenomatous Polyposis: Should Routine Ampulla Biopsies Be Performed?
Duodenal and ampullary cancers are the most common causes of death in patients with familial adenomatous polyposis (FAP) who have undergone colectomy. Current guidelines recommend
EUS-Guided Biliary Drainage: Should Antiplatelet Agents and Anticoagulants Be Stopped?
Gastroenterologists are seeing an increasing number of patients taking antiplatelet agents and/or anticoagulants (APs/ACs). Discontinuation of these agents prior to therapeutic procedures is common practice;
Antibiotics Are Not Necessary to Prevent Pancreatic Cyst Infection After Endoscopic Ultrasound-Guided Fine-Needle Aspiration
Vanessa M. Shami, MD, FASGE, reviewing Hernández JC, et al. Gastroenterology 2020 Jan 20. The European Society of Gastrointestinal Endoscopy recommends routine antibiotic prophylaxis for
Reduction in IBS Rates Using Rome IV Criteria
Vanessa M. Shami, MD, FASGE, reviewing Olafur S, et al. Gastroenterology 2020 Jan 6. Functional bowel disorders (FBDs) are common, and the diagnosis is clinical.
Gastrostomy Site Metastasis: How Common Is It?
Vanessa M. Shami, MD, FASGE, reviewing Siu J, et al. Gastrointest Endosc 2020 Jan 8. More than half of individuals with upper aerodigestive tract (UADT)
Incorporate Histologic Subtyping of Gastric Intestinal Metaplasia Into Routine Practice
Vanessa M. Shami, MD, FASGE reviewing Shah SC, et al. Gastroenterology 2019 Dec 6. Gastric cancer is the third leading cause of cancer-related mortality worldwide,
Selective Research Summary From the World Summit on Gut Microbiota for Health
Vanessa M. Shami, MD, FASGE reviewing Fuhler GM, et al. Gastroenterology 2019 Sep 6. The 2019 Gut Microbiota for Health World Summit focused on microbiota
Artificial Intelligence Could Help Early Discharge of Patients With UGI Bleeding
Prateek Sharma, MD, FASGE reviewing Shung DL, et al. Gastroenterology 2019 Sep 25. A number of clinical scoring systems (eg, the Glasgow-Blatchford, Rockall, and AIMS65)
Use of Artificial Intelligence for Blind Spots During Sedated Versus Unsedated Upper Endoscopies
Vanessa M. Shami, MD, FASGE reviewing Chen D, et al. Gastrointest Endosc 2019 Sep 18. High-resolution esophagogastroduodenoscopy (EGD) is commonly used in diagnosis and treatment
Safety and Efficacy of Peppermint Oil Treatment for IBS Tested
Peppermint oil is commonly prescribed to treat irritable bowel syndrome (IBS) without any evidence from high-quality controlled trials. This double-blind study (NCT02716285) evaluated the safety