The treatment of type 2 diabetes has evolved over the past decade, and incretin-based drugs, including dipeptidyl peptidase 4 (DPP4) inhibitors and glucagon-like peptide-1 (GLP-1)

Daily intake of low-dose aspirin increases the risk of major bleeding, but its effect on iron deficiency and anemia is less studied. This study, a

In addition to dietary modification and pharmacologic therapy, behavioral therapy has become a recognized treatment for irritable bowel syndrome (IBS) and is now integrated into

Treating bleeding malignant tumors is challenging because they tend to be diffusely friable. Hemostatic powder is a relatively new tool in the endoscopic armamentarium for

Diagnosis and resection of subcentimeter subepithelial tumors (SETs) can be challenging. One problem with endoscopic band ligation (EBL) and allowing the lesion to slough is

Helicobacter pylori eradication has been shown to decrease the risk of noncardia gastric adenocarcinoma (NCGA) in Asia; however, the data in the United States are limited.

ERCP and EUS are essential in treating a variety of disease entities. Metrics exist to measure performance quality, but data are necessary to improve quality

The development of hemostatic powders has increased the tools in our armamentarium to treat GI bleeding. However, data on their utility in peptic ulcer bleeding

In 2016, motorized spiral enteroscopy (mSe) was introduced to facilitate visualization for diagnosis and therapy of the small bowel. The primary aim of this review

Resection of duodenal adenomas (DAs) can be challenging, in part due to the thinness of the duodenal wall and its vascularity. Both postprocedural bleeding (PPB)

Eosinophilic gastrointestinal diseases (EGIDs) are rare inflammatory conditions of the GI tract characterized by tissue eosinophilia and chronic GI symptoms. EGIDs include eosinophilic gastritis (EoG)

The fecal immunochemical test (FIT) is a simple, noninvasive, at-home study that detects blood in the stool and is used for colon cancer (CRC) screening

Juvenile polyposis syndrome (JPS), in which patients develop juvenile polyps, is uncommon but is thought to be associated with an increased risk of gastrointestinal cancers.

Refractory celiac disease (RCD) is defined as celiac disease with persistent symptoms despite at least 12 months of a strict gluten-free diet. There are 2

Nonvariceal upper gastrointestinal bleeding (NVUGIB) is potentially life-threatening and a common cause of hospitalization. Endoscopy is the procedure of choice for the evaluation and management

The use of proton pump inhibitors (PPIs) has continually increased over the past 20 to 30 years. As a result, interest has grown in the

Dyspepsia is a worldwide disease that interferes with quality of life. A 2010 systematic review investigated the prevalence of endoscopic findings in patients with dyspepsia;

Abdominal pain-related disorders of gut-brain interaction (AP-DGBI) affect a sizable portion of the population. Irritable bowel syndrome (IBS) is one of the most common forms

Gastric cancer is the third most common cause of cancer-related death in the world. Through the intestinal metaplasia pathway, Helicobacter pylori is a class 1 carcinogen and

Motorized spiral enteroscopy (MSE) is innovative technology designed to facilitate advancement of the enteroscope across the small bowel. Preliminary studies have shown MSE to be

Refractory gastroparesis (RG) negatively impacts the quality of life, and treatments to date have worked variably. Gastric peroral endoscopic myotomy (G-POEM), first performed in 2013,

Proton pump inhibitors (PPIs) are prescribed for various indications, sometimes with clear evidence-based benefit and sometimes with little to no proven benefit. The purpose of

The incidence of celiac disease has been increasing over time and is commonly encountered in GI practice. Although a gluten-free diet leads to pathologic disease

Traditionally, nonampullary small-bowel adenomas ≥10 mm in diameter are resected utilizing cautery. Unfortunately, since the small bowel is thin-walled and highly vascular, adverse events are

Over the past decade, with advances in endoscopic resection (ER) techniques, there has been a trend toward removing early gastric cancer (EGC) with ER, especially

Collagenous gastritis (CG) is an uncommon disorder characterized by subepithelial collagen deposition in the stomach. Symptoms vary depending on the phenotype (pediatric-onset vs adult-onset). Treatment

Endoscopic resection (ER) of early gastric neoplasia is being performed with increasing frequency by endoscopists. Complete and accurate reporting of pathology is imperative to provide

Gastroparesis is a vexing problem and often has overlapping symptoms with functional dyspepsia. In this update from the American Gastroenterological Association, medically refractory gastroparesis is

Bleeding after endoscopic submucosal dissection (ESD) is one of the most common adverse events, but the risk of post-ESD bleeding varies, depending on antiplatelet or

Patients with atrophic gastritis (AG) are at increased risk for gastric cancer; however, the diagnosis and surveillance of AG are not well-defined. Algorithms for the

The optimal technique for gastrostomy tube placement remains undefined. This retrospective study used the Nationwide Readmissions Database and the International Classification of Diseases Procedure Coding

Underwater endoscopic mucosal resection (UEMR) has been increasingly utilized in the resection of colonic and duodenal mucosal lesions. Its use for resection of nonpolypoid superficial

A practice update from the American Gastroenterological Association used expert review and focus on methodologies to develop best practice recommendations for the management of endoscopic

Diagnosis of celiac disease has increased significantly over the past decade. The risk of cancer in this patient population is thought to be increased, although

In 2020, the U.S. Food and Drug Administration and other similar bodies recalled all ranitidine products, secondary to a possible increased association with several types

The ability of video capsule endoscopy (VCE) to detect small-bowel (SB) pathology is dependent on adequate visibility and motility. This single-center, prospective, randomized, controlled trial

Differentiating pancreatic mucinous from nonmucinous cysts can be challenging, and the pancreatic cyst fluid (PCF) carcinoembryonic antigen (CEA) level has suboptimal accuracy. Adjunct tests, such

More than 200,000 bariatric surgeries took place in 2018. Of these, 95% were either a sleeve gastrectomy or Roux-En-Y gastric bypass. Although the 90-day mortality

Patients with functional dyspepsia (FD) and gastroparesis are commonly seen, diagnosed, and treated in gastroenterology clinics. Though we think of these diseases as two separate

There has been significant media attention on the risks of proton pump inhibitors (PPIs) noted in observational studies, including associated risks of pneumonia, Clostridium difficile,

Ranitidine is a widely used H2-receptor antagonist used to treat reflux and peptic ulcer disease. Recently, the U.S. Food and Drug Association (FDA) discontinued sales

Laterally spreading lesions (LSLs) of the duodenum are increasingly being diagnosed and treated endoscopically. Although endoscopic resection of the thin and vascular duodenal wall is

Gastric outlet obstruction (GOO) can result in significant morbidity. Symptoms include early satiety, nausea, vomiting, and abdominal pain, which are frequently associated with weight loss.

Medication-refractory nausea and vomiting, which is often due to gastric dysmotility, is a challenging problem. High-frequency gastric electrical stimulation (GES), which was approved by the

Postoperative leaks are difficult to treat; however, the evolution of therapeutic endoscopy has allowed less-invasive repair techniques in an attempt to avoid repeat surgery. This

The invasive nature of the endoscopic placement of a gastrostomy tube is associated with higher morbidity and mortality compared to other routine endoscopic procedures. Alternative

The prevalence of obesity in the United States has reached an epidemic level and is associated with conditions such as insulin resistance (IR) and nonalcoholic

There are no current guidelines in the United States for gastric cancer screening, even with a high population of immigrants from Asian-Pacific countries. Studies have

Gastroparesis is a chronic medical condition that can cause unpleasant and refractory symptoms that adversely affect quality of life. Unfortunately, metoclopramide, which can cause serious

There are sufficient data in Asia to demonstrate that endoscopic submucosal dissection (ESD) has equivalent outcomes to surgical intervention for early gastric cancer (EGC). Moreover,

Duodenal and ampullary cancers are the most common causes of death in patients with familial adenomatous polyposis (FAP) who have undergone colectomy. Current guidelines recommend

Gastroenterologists are seeing an increasing number of patients taking antiplatelet agents and/or anticoagulants (APs/ACs). Discontinuation of these agents prior to therapeutic procedures is common practice;

Vanessa M. Shami, MD, FASGE, reviewing Hernández JC, et al. Gastroenterology 2020 Jan 20. The European Society of Gastrointestinal Endoscopy recommends routine antibiotic prophylaxis for

Vanessa M. Shami, MD, FASGE, reviewing Olafur S, et al. Gastroenterology 2020 Jan 6.  Functional bowel disorders (FBDs) are common, and the diagnosis is clinical.

Vanessa M. Shami, MD, FASGE, reviewing Siu J, et al. Gastrointest Endosc 2020 Jan 8. More than half of individuals with upper aerodigestive tract (UADT)

Vanessa M. Shami, MD, FASGE reviewing Shah SC, et al. Gastroenterology 2019 Dec 6. Gastric cancer is the third leading cause of cancer-related mortality worldwide,

Vanessa M. Shami, MD, FASGE reviewing Fuhler GM, et al. Gastroenterology 2019 Sep 6. The 2019 Gut Microbiota for Health World Summit focused on microbiota

Prateek Sharma, MD, FASGE reviewing Shung DL, et al. Gastroenterology 2019 Sep 25. A number of clinical scoring systems (eg, the Glasgow-Blatchford, Rockall, and AIMS65)

Vanessa M. Shami, MD, FASGE reviewing Chen D, et al. Gastrointest Endosc 2019 Sep 18.  High-resolution esophagogastroduodenoscopy (EGD) is commonly used in diagnosis and treatment

Peppermint oil is commonly prescribed to treat irritable bowel syndrome (IBS) without any evidence from high-quality controlled trials. This double-blind study (NCT02716285) evaluated the safety