Mediterranean Diet May Reduce the Risk of Crohn’s Disease Onset in Middle-Aged or Older Adults
Monika Fischer, MD, reviewing Khalili H, et al. Gut 2019 Jan 3.
A large prospective cohort study from Sweden (N=83,147; age range, 45-79 years; mean follow-up, 17 years) demonstrated a decreased incidence of late-onset Crohn’s disease in individuals who reported adherence to a modified Mediterranean diet (hazard ratio=0.42; 95% confidence interval, 0.22-0.80). The association between the Mediterranean diet and a decreased risk of developing Crohn’s disease remained significant after adjustments for age, sex, education level, body mass index, or smoking. Interestingly, there was no difference in the incidence of ulcerative colitis.
Monika Fischer, MD, FASGE
Khalili H, Håkansson N, Chan SS, et al. Adherence to a Mediterranean diet is associated with a lower risk of later-onset Crohn’s disease: results from two large prospective cohort studies. Gut 2020 Jan 3. (Epub ahead of print) (https://doi.org/10.1136/gutjnl-2019-319505)