Initial Experience With EndoRotor Tissue Resection Device

Initial Experience With EndoRotor Tissue Resection Device

Douglas K. Rex, MD, MASGE, reviewing Kaul V, et al. Gastronintest Endosc 2020 Jul 1.

The EndoRotor nonthermal powered endoscopic debridement (PED) instrument (Interscope, Inc., Whitinsville, Mass) is a new tissue resection device that can be passed through endoscopes. There is a small window in the tip of the instrument, and when suction is applied, tissue is drawn through the window then removed by a rotating cutting blade. 

The device was used with 41 lesions, of which 18 were colon polyps and 8 were Barrett’s esophagus lesions. Prior attempts at resection using standard techniques had occurred in 85.4% of the lesions. Using the PED device, technical success was achieved in 40 of the 41 lesions, with lesion eradication in 79% of the 19 lesions with follow-up examinations. There were no perforations.

Douglas K. Rex, MD, FASGE


This device is often discussed as a way to effectively resect fibrotic lesions, including those with prior unsuccessful attempts. There are a variety of other potentially successful approaches, including standard polypectomy, avulsion, endoscopic submucosal dissection, and endoscopic full-thickness resection. Ultimately, issues like cost, personal preference of the operator, and hopefully, results of controlled comparative trials will guide whether one approach is superior.

Note to readers: At the time we reviewed this paper, its publisher noted that it was not in final form and that subsequent changes might be made.


Kaul V, Diehl D, Enslin S, et al. Safety and efficacy of a novel powered endoscopic debridement tissue resection device for management of difficult colon and foregut lesions: first multicenter USA experience. Gastronintest Endosc 2020 Jul 1. (Epub ahead of print) (

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