metaplasia

GalleriesUpper GI tract

When the Z-line is not completely normal

When the Z-line is not completely normal

Depending on the patient’s degree of sedation and the examiner’s level of experience, carrying out a precise examination of the Z-line may not be very

Endoscopic techniquesTeaching VideosUpper GI tract

Endoscopic examination of a normal Z-line

Endoscopic examination of a normal Z-line

Visualization of the Z-line without enhancement and with iScan, obstructed by esophageal motility.

LiteratureUpper GI tract

Low-grade dysplasia in Barrett’s esophagus — a second opinion is important, but then treatment is needed

Low-grade dysplasia in Barrett’s esophagus — a second opinion is important, but then treatment is needed

Low-grade dysplasia (low-grade intraepithelial neoplasia, LGIN) is difficult to distinguish from inflammation histopathologically. The interobserver variance rates usually show kappa values below 0.4, representing a