Endocuff Vision Improves Detection in High Performers

Endocuff Vision Improves Detection in High Performers

Douglas K. Rex, MD, FASGE, reviewing Karsenti D, et al. Gut 2020 Mar 24.

In meta-analyses, Endocuff Vision (ECV) typically increases adenoma detection rates (ADRs) by about 7%. However, one meta-analysis found that the benefit was primarily in doctors with low ADRs.

In this French single-center study, 22 endoscopists with prior experience with ECV were divided into 2 groups. Half the endoscopists were randomized to use ECV for a period of time, then switch to standard colonoscopy without ECV, and the other group did the opposite sequence. Most of the patients had diagnostic or surveillance indications.

The mean cecal intubation time was 26 seconds shorter with ECV, and the mean withdrawal time was 36 seconds shorter. Despite that, ADRs in both groups increased by about 10%. With ECV, ADRs increased for all sections of the colon, except the rectum, where the ADR was only 1.2% higher. The most novel result was that, among doctors with baseline ADRs ≥ 25%, ECV increased ADR from 31.3% to 41.4%. ADR increased by 6.3% in doctors with baseline ADRs <25%, which did not reach significance, perhaps because there were only 6 such doctors.

Douglas K. Rex, MD, FASGE

COMMENT

The lack of an increase in ADR in the low-level detectors could be a type II error. The substantial increase in high-level detectors is consistent with at least one previous large randomized trial. In previous meta-analyses, this effect may not have been visible because another large randomized controlled trial with high detectors showed no benefit for ECV. Since high detectors probe the proximal sides of folds better, it seems logical that they would make better use of ECV in their attempts to flatten folds completely. The result of the current study is consistent with that logic.

Note to readers: At the time we reviewed this paper, its publisher noted that it was not in final form and that subsequent changes might be made.

CITATION(S)

Karsenti D, Tharsis G, Perrot B, et al. Adenoma detection by Endocuff-assisted versus standard colonoscopy in routine practice: a cluster-randomised crossover trial. Gut 2020 Mar 24. (Epub ahead of print) (https://doi.org/10.1136/gutjnl-2019-319565)

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