Endocuff Vision Defeats Cap in Tandem Study

Endocuff Vision Defeats Cap in Tandem Study

Douglas K. Rex, MD, FASGE reviewing Rameshshanker R, et al. Gastrointest Endosc 2019 Dec 10.

Recent controlled trials comparing Endocuff Vision (EV) to cap-assisted colonoscopy (CAC) have had mixed results.

In the first randomized tandem study to compare EV to CAC, 154 patients were studied. Colonoscopies were performed by 3 senior GI fellows, each of whom had previously performed more than 1500 colonoscopies. First-pass ADR (53% vs 26%) and second-pass ADR (29% vs 9%) were higher with EV compared to CAC. The overall adenoma miss rate was lower with EV (6% vs 19%). Mean adenomas per colonoscopy detected was 1.5 with EV versus 0.6 with CAC. Advanced adenoma detection was also higher with EV (21% vs 4%).

COMMENT
These results strongly favor Endocuff over cap-assisted colonoscopy. However, straight parallel-arm designs have not shown differences of this magnitude.

Note to readers: At the time we reviewed this paper, its publisher noted that it was not in final form and that subsequent changes might be made.

Douglas K. Rex, MD, FASGE

CITATION(S)

Rameshshanker R, Tsiamoulos Z, Rajendran A, et al. Endoscopic cuff-assisted colonoscopy versus cap-assisted colonoscopy in adenoma detection: randomized tandem study. Gastrointest Endosc 2019 Dec 10. (Epub ahead of print) (https://doi.org/10.1016/j.gie.2019.11.046)

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