The American College of Physicians (ACP) has issued a clinical guideline regarding acute left-sided diverticulitis. There are 3 recommendations, which were developed using the GRADE
antibiotics
antibiotics
American College of Physicians Endorses No Antibiotics for Most Uncomplicated Acute Diverticulitis
Amoxicillin-Clavulanate Favored Over Fluoroquinolone-Metronidazole for Outpatient Diverticulitis
A combination of fluoroquinolone (ciprofloxacin, levofloxacin) and metronidazole is the most commonly used antibiotic treatment for outpatient diverticulitis. However, the U.S. Food and Drug Administration
Appendicitis Treatments: Large Randomized Controlled Trial Compares Antibiotics With Appendectomy
Antibiotic treatment is now widely recognized as an option for appendicitis therapy. In a nonblinded randomized trial of 1552 adults, including 414 with an appendicolith,
No Benefit From Antibiotics for Uncomplicated Diverticulitis
A randomized, placebo-controlled, double-blinded trial showed no benefit from antibiotic therapy for the management of uncomplicated acute diverticulitis. Hospitalized patients (N=180) in New Zealand and