Following total proctocolectomy with restorative ileal pouch-anal anastomosis (IPAA) for ulcerative colitis (UC), about one-third of patients develop chronic pouchitis. Treatment of antibiotic-refractory and Crohn’s
anti-TNF
anti-TNF
Recycled Precolectomy Anti-Tumor Necrosis Factor Does Not Work for Chronic Pouchitis
Anti-Tumor Necrosis Factor Should Be Considered for Ulcerative Proctitis Refractory to Conventional Therapy
Monika Fischer, MD, reviewing Pineton de Chambrun G, et al. Clin Gastroenterol Hepatol 2020 Mar. Treatment of ulcerative proctitis that is unresponsive to mesalamine and
Crohn’s Disease Patients with HLA-DQA1*05 Allele at Increased Risk of Antidrug Antibody Development
Monika Fischer, MD, reviewing Sazonovs A, et al. Gastroenterology 2020 Jan. In this genome-wide association study, 1240 patients with biologic-naive Crohn’s disease were treated with