Multicenter International Study Confirms That Snare-Tip Soft Coagulation of EMR Margin Dramatically Lowers Recurrence Rate
Douglas K. Rex, MD, MASGE, reviewing Sidhu M, et al. Gastroenterology 2021 Mar 30.
A previous randomized controlled trial showed that thermal ablation of a normal-appearing EMR margin after complete polyp resection reduced the recurrence rate from 21% to 5%. Since then, emphasis has been placed on the need for a systematic, complete ablation of the entire margin. In a follow-up uncontrolled study of 1037 nonpedunculated lesions ≥20 mm in size, removed at multiple centers in several countries, the recurrence rate at follow-up was 1.4%.
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CITATION(S)
Sidhu M, Shahidi N, Gupta S, et al. Outcomes of thermal ablation of the mucosal defect margin after endoscopic mucosal resection: a prospective, international, multi-centre trial of 1000 large non-pedunculated colorectal polyps. Gastroenterology 2021 Mar 30. (Epub ahead of print) (https://doi.org/10.1053/j.gastro.2021.03.044)