Daily 81 mg of Aspirin OK in Patients With IBD

Monika Fischer, MD, reviewing Patel P, et al. Inflamm Bowel Dis 2020 Mar 27.

Nonsteroidal anti-inflammatory medications are known to increase the risk of IBD flare; however, little is known about the safety of daily aspirin use. Researchers analyzed data from 174 patients with IBD who were taking aspirin daily and compared it to 696 matched controls in a single center’s registry. Daily use of 81 mg of aspirin (N=129) was not associated with higher rates of IBD-related hospitalizations (odds ratio [OR], 1.09; 95% confidence interval [CI], 0.61-1.93; P=.71), surgeries (OR, 0.89; 95% CI, 0.38-1.66; P=.66), or corticosteroid prescriptions (OR, 0.73; 95% CI, 0.42-1.74; P=.13). However, patients on higher doses of aspirin were more likely to be given a corticosteroid prescription when compared with those receiving 81 mg of aspirin (OR, 3.36; 95% CI, 1.55-6.82; P=.003).

Monika Fischer, MD, FASGE

CITATION(S )

Patel P, Gao G, Gulotta G, et al. Daily aspirin use does not impact clinical outcomes in patients with inflammatory bowel disease. Inflamm Bowel Dis 2020 Mar 27. (Epub ahead of print) (https://doi.org/10.1093/ibd/izaa060)