In a retrospective analysis of all multitarget stool DNA (mt-sDNA) tests ordered at a single center over one year by 62 primary care providers (50 physicians and 12 nurse practitioners), mt-sDNA was ordered for 902 patients. About 27% of patients never returned the sample or had an indeterminate result and did not resubmit a test. Of completed tests, the positivity rate was 18.9%, but 23% of patients with positive results did not complete diagnostic colonoscopy, although the provider recommended it in 97% of cases.<\/p>\n\n\n\n
Of all 902 orders, 17.7% were for off-label indications. Increasing age was associated with higher odds of an off-label order (odds ratio, 2.32 for each 10-year age increase). A positive test result was associated with older age and having a baseline indication for diagnostic colonoscopy. The latter was associated with a 3-fold increased chance of a positive result. Among the practitioners, ordering tests for off-label indications ranged from 0% to 71%.<\/p>\n","protected":false},"excerpt":{"rendered":"
In a retrospective analysis of all multitarget stool DNA (mt-sDNA) tests ordered at a single center over one year by 62 primary care providers (50 physicians and 12 nurse practitioners), mt-sDNA was ordered for 902 patients. About 27% of patients never returned the sample or had an indeterminate result and did not resubmit a test. … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,2634,2635,2636],"class_list":["post-9988","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-mt-sdna","tag-multitarget-stool-dna","tag-off-label"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/9988","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=9988"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=9988"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=9988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}