Laterally spreading lesions (LSLs) of the duodenum are increasingly being diagnosed and treated endoscopically. Although endoscopic resection of the thin and vascular duodenal wall is technically challenging, endoscopic mucosal resection (EMR) is easier than endoscopic submucosal dissection at the expense of increased recurrence. This prospectively collected, single-center, observational study assessed whether thermal ablative therapy at the resection margins after EMR (EMR-T) reduces recurrence at the first 6-month surveillance endoscopy. <\/p>\n\n\n\n
Fifty-four patients with duodenal LSLs >10 mm were consecutively enrolled in the EMR-T group over 43 months (March 2016-October 2019). Snare-tip soft-coagulation (effect 4, 80 watts; ERBE, T\u00fcbingen, Germany) was utilized around the circumference of the EMR defect. The aim was to create a 2-mm to 3-mm rim of completely ablated tissue. The EMR-T cohort was compared with a historic cohort of 125 LSLs treated by conventional EMR before March 2016. Recurrence was significantly lower in the EMR-T group versus the conventional EMR group (1\/49 [2.3%] vs 19\/108 [17.6%]; P<\/em>=.01). Additionally, there were no differences in technical success, adverse events, or need to refer to surgery.<\/p>\n","protected":false},"excerpt":{"rendered":" Laterally spreading lesions (LSLs) of the duodenum are increasingly being diagnosed and treated endoscopically. Although endoscopic resection of the thin and vascular duodenal wall is technically challenging, endoscopic mucosal resection (EMR) is easier than endoscopic submucosal dissection at the expense of increased recurrence. This prospectively collected, single-center, observational study assessed whether thermal ablative therapy at … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1789],"tags":[268,1832,2596,2597,2103],"class_list":["post-9805","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-stomach-and-small-bowel","tag-emr","tag-endoscopic-mucosal-resection-2","tag-laterally-spreading-lesions","tag-lsls","tag-stomach-2"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/9805","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=9805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=9805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=9805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}