In various series, 2% to 7% of patients with colorectal cancer (CRC) have either synchronous or metachronous second cancer. Second CRCs have generally been considered to be independent primary cancers. In a study of 24 patients, each with two diagnoses of CRC, DNA analysis indicated that one tumor was a clone of the other in 8 patients.<\/p>\n\n\n\n
Although the mechanism of spread is unclear, the authors believe it might be associated with intraluminal spread, perhaps to sites of injury (eg, diverticulitis or iatrogenic injury).<\/p>\n","protected":false},"excerpt":{"rendered":"
In various series, 2% to 7% of patients with colorectal cancer (CRC) have either synchronous or metachronous second cancer. Second CRCs have generally been considered to be independent primary cancers. In a study of 24 patients, each with two diagnoses of CRC, DNA analysis indicated that one tumor was a clone of the other in … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,1823,1343],"class_list":["post-9784","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-colorectal-cancer","tag-crc"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/9784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=9784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=9784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=9784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}