{"id":9783,"date":"2021-01-10T16:22:41","date_gmt":"2021-01-10T15:22:41","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=9783"},"modified":"2021-01-10T16:22:42","modified_gmt":"2021-01-10T15:22:42","slug":"hydrogen-peroxide-one-way-or-another-appears-beneficial-during-endoscopic-necrosectomy","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/hydrogen-peroxide-one-way-or-another-appears-beneficial-during-endoscopic-necrosectomy\/","title":{"rendered":"Hydrogen Peroxide, One Way or Another, Appears Beneficial During Endoscopic Necrosectomy"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Management of walled-off pancreatic necrosis often benefits from direct transmural endoscopic necrosectomy. This retrospective chart review assessed the utility of hydrogen peroxide (H2O2) lavage as an ancillary intervention during endoscopic necrosectomy at 9 centers over a 7-year interval. Overall, technical success was achieved in all 204 patients included in the study, and clinical success (resolution within 6 months) was achieved in 81% (166\/189). The clinical success rate was higher with the use of H2O2 lavage during endoscopic necrosectomy than without (93.8% vs 78.9%; <em>P<\/em>=.002), when administered using highly varied parameters and techniques. Multivariate analysis of a smaller matched subset of study patients confirmed both higher clinical success (odds ratio [OR], 3.33; <em>P<\/em>=.033) and earlier resolution (OR, 2.27;<em> P<\/em>&lt;.001), with no difference in overall complication rates (5.2% vs 7.7%; <em>P<\/em>=.30), postprocedure bleeding (7 vs 9; <em>P<\/em>=.25), infection (1 vs 2; <em>P<\/em>=.58), or perforation (2 vs 3; <em>P<\/em>=.66). Procedures employing H2O2 lavage were shorter than those without (52.0 \u00b1 35.0 minutes vs 72.8 \u00b1 45.6 minutes; <em>P<\/em>&lt;.001).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Management of walled-off pancreatic necrosis often benefits from direct transmural endoscopic necrosectomy. This retrospective chart review assessed the utility of hydrogen peroxide (H2O2) lavage as an ancillary intervention during endoscopic necrosectomy at 9 centers over a 7-year interval. Overall, technical success was achieved in all 204 patients included in the study, and clinical success (resolution &#8230; <a title=\"Hydrogen Peroxide, One Way or Another, Appears Beneficial During Endoscopic Necrosectomy\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/hydrogen-peroxide-one-way-or-another-appears-beneficial-during-endoscopic-necrosectomy\/\" aria-label=\"Read more about Hydrogen Peroxide, One Way or Another, Appears Beneficial During Endoscopic Necrosectomy\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,67],"tags":[2582,2581,2583,2128],"class_list":["post-9783","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-bauchspeicheldruese-pankreas","tag-h2o2","tag-hydrogen-peroxide","tag-necrosectomy-2","tag-pancreatobiliary"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/9783","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=9783"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=9783"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=9783"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}