Antibiotic treatment is now widely recognized as an option for appendicitis therapy.<\/p>\n\n\n\n
In a nonblinded randomized trial of 1552 adults, including 414 with an appendicolith, there was no difference in the primary outcome of 30-day health status on a quality-of-life measure between antibiotics and appendectomy. Patients were excluded for septic shock, peritonitis, recurrent appendicitis, perforation, severe phlegmon or walled-off abscess, or evidence of neoplasm on imaging. Patients in the antibiotics arm were administered antibiotics intravenously for 24 hours, for which 51% were hospitalized at least briefly.<\/p>\n\n\n\n
In the antibiotics group, appendectomy was performed in 11% of the patients by 48 hours, 20% by 30 days, and 29% by 90 days. Those with an appendicolith in the antibiotics arm were more likely than patients without an appendicolith to need appendectomy (41% vs 25%). After the index treatment, patients in the antibiotics arm were more likely than patients in the appendectomy group to visit the emergency department (9% vs 4%) and more likely to be hospitalized (including for eventual appendectomy; 24% vs 5%). Among the other outcomes, the antibiotics group missed fewer workdays (5.26 vs 8.73), and neoplasms were found more often in the appendectomy group (7 vs 2). <\/p>\n\n\n\n
Complications occurred in 8.1% of the antibiotics group versus 3.5% of the appendectomy group, attributable to those with an appendicolith (20.2% vs 3.6%) and not to those without an appendicolith (3.7% vs 3.5%). Subcutaneous drains were also needed more often in the antibiotics group than the appendectomy group (2.5% vs 0.5%).<\/p>\n","protected":false},"excerpt":{"rendered":"
Antibiotic treatment is now widely recognized as an option for appendicitis therapy. In a nonblinded randomized trial of 1552 adults, including 414 with an appendicolith, there was no difference in the primary outcome of 30-day health status on a quality-of-life measure between antibiotics and appendectomy. Patients were excluded for septic shock, peritonitis, recurrent appendicitis, perforation, … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2051,2561,2058],"class_list":["post-9693","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-antibiotics","tag-appendicitis-therapy","tag-colon-2"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/9693","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=9693"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=9693"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=9693"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}