In any screening program, it is important to know the benefits and harms of screening. Patients who have a positive fecal immunochemical test (FIT) result have a high yield of colonoscopy. The death rate from colonoscopy in FIT-positive patients is uncertain. <\/p>\n\n\n\n
In a study of the Netherlands’ national FIT screening program, 172,797 persons underwent colonoscopy, of whom 13,848 (8%) had colorectal cancer (CRC) identified. <\/p>\n\n\n\n
Fatalities from colonoscopy were measured in 3 ways. First, compulsory reporting of fatal colonoscopy-related complications identified 4 deaths, or 0.23 per 10,000 participants, or 1 per 43,199 colonoscopy patients. <\/p>\n\n\n\n
Second, to understand excess all-cause mortality, the death rate from national registries in the FIT-positive patients undergoing colonoscopy who did not have CRC identified was compared to the FIT-negative patients in the program. The excess all-cause mortality in the patients undergoing colonoscopy was 0.91 per 10,000 participants, for an excess death rate of 1 per 10,961 colonoscopy patients.<\/p>\n\n\n\n
Third, the authors evaluated cause of death in a segment of 112,634 FIT-positive patients who had colonoscopy, of whom 48 died within 30 days after colonoscopy. Of these 48 patient deaths, 10 (20.8%) appeared likely to be related to the colonoscopy, 3 were caused by sepsis, 5 resulted from cardiovascular events within 6 days of colonoscopy, and 2 occurred from an endoscopic intervention between 8 and 30 days. This led to a calculation of 0.89 deaths per 10,000 FIT-positive persons, or 1 per 11,236 FIT-positive patients undergoing colonoscopy.<\/p>\n","protected":false},"excerpt":{"rendered":"
In any screening program, it is important to know the benefits and harms of screening. Patients who have a positive fecal immunochemical test (FIT) result have a high yield of colonoscopy. The death rate from colonoscopy in FIT-positive patients is uncertain. In a study of the Netherlands’ national FIT screening program, 172,797 persons underwent colonoscopy, … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,1858],"class_list":["post-8852","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-fit-crc"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/8852","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=8852"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=8852"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=8852"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}