{"id":8299,"date":"2020-06-15T11:29:28","date_gmt":"2020-06-15T09:29:28","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=8299"},"modified":"2020-06-15T11:29:30","modified_gmt":"2020-06-15T09:29:30","slug":"lynch-syndrome-testing-on-preoperative-biopsy-specimens-is-accurate","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/lynch-syndrome-testing-on-preoperative-biopsy-specimens-is-accurate\/","title":{"rendered":"Lynch Syndrome Testing on Preoperative Biopsy Specimens Is Accurate"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">In this study, there were 96 patients with matched preoperative and postoperative immunohistochemistry (IHC) and microsatellite instability testing results for Lynch syndrome. The concordance of IHC testing between preoperative and postoperative specimens was 100% for&nbsp;<em>MLH1<\/em>, 100% for&nbsp;<em>MSH2<\/em>, 97.1% for&nbsp;<em>MSH6<\/em>, and 98.8% for&nbsp;<em>PMS2<\/em>.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In the total group of persons tested preoperatively, 2 of the 8 patients underwent subtotal colectomy compared to none of the 10 patients who were tested postoperatively. One of the 5 women in the preoperative group underwent hysterectomy and oophorectomy compared to none of the 6 women in the postoperative group.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In this study, there were 96 patients with matched preoperative and postoperative immunohistochemistry (IHC) and microsatellite instability testing results for Lynch syndrome. The concordance of IHC testing between preoperative and postoperative specimens was 100% for&nbsp;MLH1, 100% for&nbsp;MSH2, 97.1% for&nbsp;MSH6, and 98.8% for&nbsp;PMS2.&nbsp; In the total group of persons tested preoperatively, 2 of the 8 patients &#8230; <a title=\"Lynch Syndrome Testing on Preoperative Biopsy Specimens Is Accurate\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/lynch-syndrome-testing-on-preoperative-biopsy-specimens-is-accurate\/\" aria-label=\"Read more about Lynch Syndrome Testing on Preoperative Biopsy Specimens Is Accurate\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,2059],"class_list":["post-8299","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-ihc"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/8299","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=8299"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=8299"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=8299"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}