Post-ERCP pancreatitis (PEP) remains an important adverse event. Indomethacin suppositories and pancreatic duct (PD) stents have both been demonstrated to reduce PEP in patients at high risk for PEP. The authors of this study sought to measure the use of these treatments and to correlate them with the incidence of PEP in broad clinical practice of ERCP. From a commercial database encompassing 26 U.S. health care systems, they identified 26,820 ERCPs performed in narrowly defined high-risk patients over a 10-year period (2009-2018), surrounding the 2012 publication of data on the benefit of prophylactic indomethacin. PEP, defined as a diagnosis of pancreatitis during an emergency room or hospital admission within 5 days of ERCP, occurred in 8.6% of patients. The PEP rate did not decline during the 2012 to 2018 interval, whereas PD stent placement declined quickly after 2012 (40.7% in 2013; 8.5% in 2014; nadir, 3.0%), and indomethacin usage increased in a linear fashion but did not exceed 50% in high-risk patients by 2018.<\/p>\n","protected":false},"excerpt":{"rendered":"
Post-ERCP pancreatitis (PEP) remains an important adverse event. Indomethacin suppositories and pancreatic duct (PD) stents have both been demonstrated to reduce PEP in patients at high risk for PEP. The authors of this study sought to measure the use of these treatments and to correlate them with the incidence of PEP in broad clinical practice … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1840],"tags":[379,2049],"class_list":["post-7946","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-bauchspeicheldruese","tag-pep","tag-post-ercp"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/7946","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=7946"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=7946"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=7946"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}