{"id":6928,"date":"2019-11-18T07:22:41","date_gmt":"2019-11-18T06:22:41","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=6928"},"modified":"2019-11-25T07:56:28","modified_gmt":"2019-11-25T06:56:28","slug":"colon-capsule-doesnt-help-in-fit-positive-patients","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/colon-capsule-doesnt-help-in-fit-positive-patients\/","title":{"rendered":"Colon Capsule Doesn\u2019t Help in FIT-Positive Patients"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><em><strong>Douglas K. Rex, MD, FASGE reviewing Pecere S, et al. Gastrointest Endosc 2019 Oct 17.<\/strong><\/em><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In some European countries with limited colonoscopy resources, capsule colonoscopy has been proposed as a triage screen in patients with fecal immunochemical test (FIT) positivity.&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In a study from 4 screening centers in Italy and Spain, 222 FIT-positive patients were enrolled. Of these patients, 19.8% had an inadequate capsule colonoscopy study, including 8.6% (n=19) who refused to swallow the capsule and 11.3% (n=25) in whom the capsule did not pass through the full colon. Of 178 patients who had both full capsule and conventional colonoscopies, 69.7% had a polyp detected by capsule, including 6.2% (n=11) with cancer and 27.5% (n=49) with advanced adenoma (including sessile serrated polyp \u226510 mm). Using liberal polyp matching rules on a per-patient basis, with a 6-mm cutoff for referral, 52.8% of patients would be referred for colonoscopy (there were 40 patients with false-positive capsule studies). Sensitivity and specificity for advanced neoplasia were 90% and 66.1%, respectively.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At a 10-mm threshold for referral for colonoscopy, sensitivity and specificity for advanced neoplasia were 76.7% and 90.7%, respectively.<\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<figure class=\"wp-block-pullquote\" style=\"border-color:#bd6fb7\"><blockquote><p> COMMENT<br> These results indicate that capsule use is not a good option in FIT-positive patients due to high rates of technically inadequate capsule studies, low sensitivity, and high rates of referral for colonoscopy. In general, capsule colonoscopy is best for screening in low-prevalence populations, in patients who refuse colonoscopy, or in those who appear high risk for sedation.<\/p><\/blockquote><\/figure>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Note to readers: At the time we reviewed this paper, its publisher noted that it was not in final form and that subsequent changes might be made. <\/p>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"wp-block-media-text alignwide\" style=\"grid-template-columns:27% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"188\" src=\"https:\/\/www.endoscopy-campus.com\/wp-content\/uploads\/d-rex.jpg\" alt=\"\" class=\"wp-image-5921\"\/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"has-large-font-size wp-block-paragraph\">Douglas K. Rex, MD, FASGE <\/p>\n<\/div><\/div>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">CITATION(S) <\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"> Pecere S, Senore C, Hassan C, et al. Accuracy of colon capsule for advanced neoplasia.<em>&nbsp;Gastrointest Endosc<\/em>&nbsp;2019 Oct 17. (Epub ahead of print) (<a rel=\"noreferrer noopener\" href=\"https:\/\/doi.org\/10.1016\/j.gie.2019.09.041\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.gie.2019.09.041<\/a>) <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Douglas K. Rex, MD, FASGE reviewing Pecere S, et al. Gastrointest Endosc 2019 Oct 17. In some European countries with limited colonoscopy resources, capsule colonoscopy has been proposed as a triage screen in patients with fecal immunochemical test (FIT) positivity.&nbsp;&nbsp; In a study from 4 screening centers in Italy and Spain, 222 FIT-positive patients were &#8230; <a title=\"Colon Capsule Doesn\u2019t Help in FIT-Positive Patients\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/colon-capsule-doesnt-help-in-fit-positive-patients\/\" aria-label=\"Read more about Colon Capsule Doesn\u2019t Help in FIT-Positive Patients\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[],"class_list":["post-6928","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/6928","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=6928"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=6928"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=6928"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}