Long-term exposure to PM2.5 (fine particulate matter) is a known risk factor for lung cancer. However, the evidence linking PM2.5 to esophageal cancer is sparse and inconclusive. Long-term exposure to PM2.5 can cause chronic low-grade inflammation and oxidative stress locally and systemically, which can trigger genetic changes that increase the risk of lung and non-lung cancer.<\/p>\n\n\n\n
The study analyzed China’s Kadoorie Biobank and identified 510,125 participants who did not have esophageal cancer at the start. The study used a satellite-based model to estimate PM2.5 exposure during the study period. Using a Cox proportional hazard model, the study found a linear concentration-response relationship between PM2.5 exposure and esophageal cancer. For each 10 \u03bcg\/m3 increase in PM2.5, the hazard ratio was 1.16 (95% confidence interval, 1.04-1.30) for esophageal cancer incidence. The study also found that the population-attributable risk due to PM2.5 exposure was higher than that due to lifestyle risk factors.<\/p>\n","protected":false},"excerpt":{"rendered":"
Long-term exposure to PM2.5 (fine particulate matter) is a known risk factor for lung cancer. However, the evidence linking PM2.5 to esophageal cancer is sparse and inconclusive. Long-term exposure to PM2.5 can cause chronic low-grade inflammation and oxidative stress locally and systemically, which can trigger genetic changes that increase the risk of lung and non-lung … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1791],"tags":[3720,3719,2098,3718],"class_list":["post-14205","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-esophagus","tag-air-pollution","tag-chinas-kadoorie-biobank","tag-esophagus-2","tag-pm2-5"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/14205","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=14205"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=14205"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=14205"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}