In 3 U.S. centers, asymptomatic patients aged 50 to 69 years (or 40-69 if Black) were randomized to screening colonoscopy or annual sequential high-sensitivity guaiac fecal occult blood testing (HSgFOBT). Importantly, all aspects of the trial were facilitated by coordinators. In the colonoscopy arm, 83.6% of patients completed the baseline examination. In the HSgFOBT arm, 73.1% completed the baseline test, but only 38% completed successive annual rounds.<\/p>\n\n\n\n
In the screening-colonoscopy arm, any adenoma or serrated lesion was found in 22.7% of participants. Among those who were adherent to the protocol, either cancer or an advanced adenoma or advanced serrated lesion was found in 8.2% in the colonoscopy arm versus 3.3% in the HSgFOBT arm.<\/p>\n\n\n\n
Among those who were never positive in the HSgFOBT arm, 30% overall crossed over to colonoscopy, including 39.8% at one center, and 5.5% of crossovers had an advanced lesion.<\/p>\n","protected":false},"excerpt":{"rendered":"
In 3 U.S. centers, asymptomatic patients aged 50 to 69 years (or 40-69 if Black) were randomized to screening colonoscopy or annual sequential high-sensitivity guaiac fecal occult blood testing (HSgFOBT). Importantly, all aspects of the trial were facilitated by coordinators. In the colonoscopy arm, 83.6% of patients completed the baseline examination. In the HSgFOBT arm, … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,3685,3687,3686],"class_list":["post-13998","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-guaiac-fecal-testing","tag-high-sensitivity-guaiac-fecal-occult-blood-testing","tag-hsgfobt"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13998","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13998"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13998"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13998"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}