Some studies suggest that prior treatment may increase the difficulty and success of tunneling during a peroral endoscopic myotomy (POEM) procedure, but recent studies have demonstrated similar outcomes between treatment-na\u00efve patients and those with treatment failure undergoing POEM. The current study aimed to determine whether prior treatment with Botox, pneumatic dilation (PD), or laparoscopic heller myotomy (LHM) was associated with longer procedure times, increased failure rates, or a lower rate of symptomatic relief in patients undergoing POEM for achalasia or spastic esophageal pathologies. <\/p>\n\n\n\n
The study included 95 patients (mean age 55.6 years, 45% female) who underwent POEM for achalasia and spastic esophageal pathologies between February 2017 and September 2021. Of the POEM procedures, 25 were for type I achalasia, 31 for type II, and 33 for spastic esophageal pathologies. Patients with prior treatment by Botox (n=18), dilation (n=17), or LHM (n=3) were designated as the \u201ctreatment-refractory\u201d group, and those without prior treatment as the \u201ctreatment-na\u00efve group.\u201d The primary outcomes were clinical success and procedure difficulty, with data collected on patient demographics, previous treatment, preprocedure and postprocedure Eckardt scores (ES), distensibility indices, and procedure times. <\/p>\n\n\n\n
The study found that prior treatment with Botox injections, PD, or LHM was associated with decreased case time and easier tunneling during POEM, and there was no significant difference in post-ES or technical success between the groups.<\/p>\n","protected":false},"excerpt":{"rendered":"
Some studies suggest that prior treatment may increase the difficulty and success of tunneling during a peroral endoscopic myotomy (POEM) procedure, but recent studies have demonstrated similar outcomes between treatment-na\u00efve patients and those with treatment failure undergoing POEM. The current study aimed to determine whether prior treatment with Botox, pneumatic dilation (PD), or laparoscopic heller … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1791],"tags":[1515,2098,3656,3277,2578,237,3655],"class_list":["post-13929","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-esophagus","tag-botox","tag-esophagus-2","tag-lhm","tag-pd","tag-peroral-endoscopic-myotomy-2","tag-poem","tag-prior-achalasia-treatment"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13929","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13929"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13929"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13929"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}