In a very large study, 11.8% of 77,007 patients receiving antithrombotic treatment had a positive fecal immunochemical test (FIT) result, compared with 6% of those receiving no treatment. The relative risk of a positive FIT was increased with every class of agents, including aspirin (1.22), warfarin (1.60), direct oral acting anticoagulant (DOAC; 2.40), antiplatelet therapy (1.18), warfarin plus antiplatelet therapy (2.14), dual antiplatelet therapy (1.34), and triple therapy (any 3 drugs; 2.36).<\/p>\n\n\n\n
The positive predictive value (PPV) for cancer was 6.4% in patients not receiving antithrombotic treatment. The PPV for cancer was reduced by 60% in patients taking DOACs and 64% in patients receiving triple therapy, but there was some reduction across the board of anticoagulants. The absolute risk rates of cancer with a positive FIT for patients receiving DOACs and triple therapy were 3.3% and 3.0%, respectively. The risk of cancer or any high-risk adenoma in FIT-positive patients was also reduced, with the greatest reduction of 42% in patients receiving DOACs.<\/p>\n","protected":false},"excerpt":{"rendered":"
In a very large study, 11.8% of 77,007 patients receiving antithrombotic treatment had a positive fecal immunochemical test (FIT) result, compared with 6% of those receiving no treatment. The relative risk of a positive FIT was increased with every class of agents, including aspirin (1.22), warfarin (1.60), direct oral acting anticoagulant (DOAC; 2.40), antiplatelet therapy … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[3621,3622,2058,1898,3570,3571],"class_list":["post-13848","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-anticoagulant","tag-antiplatelet","tag-colon-2","tag-fit","tag-positive-predictive-value","tag-ppv"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13848","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13848"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13848"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13848"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}