Per the Lyon Consensus, endoscopic documentation of Los Angeles (LA) grade C or D esophagitis is conclusive evidence of GERD, whereas LA grades A and B esophagitis are inconclusive for a GERD diagnosis, and further testing is required. The primary aim of the current study was to evaluate symptomatic patients with LA grade A, B, or C esophagitis and compare findings from multichannel intraluminal impedance and pH (MII-pH) monitoring to determine whether patients with a specific LA grade esophagitis provide objective GERD evidence. <\/p>\n\n\n\n
In this multicenter retrospective study, 155 patients (81 females; median age, 52 years; median body mass index, 26) met the inclusion criteria. Patient age, lifestyle\/dietary habits, and clinical presentation were similar across the patients separated into 3 groups according to their LA grade of esophagitis (LA grade A=74; LA grade B=61; LA grade C=20). <\/p>\n\n\n\n
Using MII-pH monitoring, 17.6% of patients with grade A esophagitis, 100% with grade B, and 75% with grade C had objective evidence of GERD. Using pH metry, the acid exposure time of >6% was seen in 1.4%, 52.5%, and 75% of patients with LA grades A, B, and C esophagitis, respectively. With the use of MII-pH data, an additional 16.2% of patients with LA grade A and 47.5% with LA grade B esophagitis had an acid exposure time of 4% to 6%. Finally, compared with patients with LA grade C esophagitis, 100% of those with LA grade B esophagitis had objective GERD versus only 17.6% with LA grade A esophagitis (P<\/em><.001).<\/p>\n","protected":false},"excerpt":{"rendered":" Per the Lyon Consensus, endoscopic documentation of Los Angeles (LA) grade C or D esophagitis is conclusive evidence of GERD, whereas LA grades A and B esophagitis are inconclusive for a GERD diagnosis, and further testing is required. The primary aim of the current study was to evaluate symptomatic patients with LA grade A, B, … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1791],"tags":[2098,2070,3599,3598],"class_list":["post-13715","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-esophagus","tag-esophagus-2","tag-gerd-2","tag-la-grade","tag-lyon-consensus"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13715"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13715"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}