{"id":13649,"date":"2023-01-23T13:57:49","date_gmt":"2023-01-23T12:57:49","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=13649"},"modified":"2023-01-23T13:57:50","modified_gmt":"2023-01-23T12:57:50","slug":"fit-fecal-dna-test-had-high-positive-predictive-value-in-second-round-screening","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/fit-fecal-dna-test-had-high-positive-predictive-value-in-second-round-screening\/","title":{"rendered":"FIT-Fecal DNA Test Had High Positive Predictive Value in Second-Round Screening"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">This study examined the positive predictive value (PPV) of a second round of screening with a fecal immunochemical test (FIT)-fecal DNA test (Cologuard, Exact Sciences). The study included 2758 patients who had a negative baseline test at a median of 3.2 years earlier. Fifty-eight percent had a colonoscopy at a median of 10.4 years before their first FIT-fecal DNA test, but only 1.1% of those patients had a prior low-risk adenoma.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The overall positivity rate in the second round of screening was 15.3%. The PPV was 0.25% for colorectal cancer (CRC), 24% for advanced lesions (advanced adenomas, sessile serrated lesions [SSLs] \u22651 cm, or SSLs with dysplasia), and 67% for any colorectal neoplasia.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In comparison, PPVs in first-round screening in another cohort were 1% for CRC and 28% for advanced lesions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This study examined the positive predictive value (PPV) of a second round of screening with a fecal immunochemical test (FIT)-fecal DNA test (Cologuard, Exact Sciences). The study included 2758 patients who had a negative baseline test at a median of 3.2 years earlier. Fifty-eight percent had a colonoscopy at a median of 10.4 years before &#8230; <a title=\"FIT-Fecal DNA Test Had High Positive Predictive Value in Second-Round Screening\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/fit-fecal-dna-test-had-high-positive-predictive-value-in-second-round-screening\/\" aria-label=\"Read more about FIT-Fecal DNA Test Had High Positive Predictive Value in Second-Round Screening\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,1823,1343,3441,1826,3569,3570,3571],"class_list":["post-13649","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-colorectal-cancer","tag-crc","tag-dna","tag-fecal-immunochemical-test","tag-fit-fecal","tag-positive-predictive-value","tag-ppv"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13649","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13649"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13649"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13649"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}