Tissue sampling of subepithelial lesions (SELs) is needed to determine the diagnosis, malignant potential, and management of these lesions. Endoscopic ultrasound-guided fine needle aspiration and\/or biopsy (EUS-FNA and\/or FNB) is the most common procedure for tissue acquisition. Bite-on-bite and single-incision with needle-knife (SINK) biopsies have emerged as alternative diagnostic approaches for tissue acquisition, eliminating the need for EUS. This systematic review and meta-analysis evaluated the technical and diagnostic success (primary outcomes) as well as the adverse events (secondary outcomes) of SINK biopsy. <\/p>\n\n\n\n
The authors of this study searched numerous databases and performed a meta-analysis of 7 studies with a total of 219 SINK biopsy procedures. The technical success rate of SINK was 98.1% (95% confidence interval [CI], 94.9%-99.3%; P<\/em>=.000; I2=0.0%), and the diagnostic success rate was 87.9% (95% CI, 82.6%-91.7%; P<\/em>=.000; I2=0.0%). Immunohistochemical staining was successfully performed in 88.3% of patients (95% CI, 78.7%-93.9%; P<\/em>=.000; I2=3.5%). Adverse events occurred in 7.5% of patients (95% CI, 4.3%-12.7%; P<\/em>=.00; I2=7.2%), with bleeding being the most common (9 cases of bleeding, 1 case of abdominal pain).<\/p>\n","protected":false},"excerpt":{"rendered":" Tissue sampling of subepithelial lesions (SELs) is needed to determine the diagnosis, malignant potential, and management of these lesions. Endoscopic ultrasound-guided fine needle aspiration and\/or biopsy (EUS-FNA and\/or FNB) is the most common procedure for tissue acquisition. Bite-on-bite and single-incision with needle-knife (SINK) biopsies have emerged as alternative diagnostic approaches for tissue acquisition, eliminating the … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,2052],"tags":[625,1610,3558,3556,3557,3559,3560],"class_list":["post-13579","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-eus","tag-eus","tag-eus-fna","tag-fnb","tag-sampling-of-subepithelial-lesions","tag-sels","tag-single-incision-with-needle-knife","tag-sink"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13579","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13579"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13579"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13579"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}