Although small (<2 cm), nonfunctioning pancreatic neuroendocrine tumors (PNETs) are typically followed, there are instances, such as patient anxiety, that prompt resection. Endoscopic ultrasound-guided ethanol ablation (EUS-EA) has been used as an alternative modality to surgery to treat PNETs. This propensity score-matching study aimed to compare the safety and long-term outcomes of EUS-EA with those of surgery for the management of nonfunctioning, small PNETs. <\/p>\n\n\n\n
The study included 97 patients who underwent EUS-EA and 188 who underwent surgery at a single medical center. Propensity score matching resulted in 89 matched pairs. Early (within 14 days) major complications were significantly lower in patients who underwent EUS-EA versus surgery (0% vs 11.2%; P<\/em>=.003). There was no statistical difference in late (after 14 days) complications (3.4% vs 10.1%; P<\/em>=.07). Both treatment modalities had similar 10-year overall and disease-specific survival rates. The average number of days spent in the hospital was significantly less in the EUS-EA group (4 days vs 14.1 days; P<\/em><.001), and endocrine pancreatic insufficiency occurred less often after EUS-EA (33.3% vs 48.6%; P<\/em>=.121). <\/p>\n\n\n\n It is important to note that in the EUS-EA group, only 64.9% of patients showed complete ablation (defined as no suspicious viable tumor at the time of radiologic evaluation), and 46% of those showed local recurrence after complete ablation.<\/p>\n","protected":false},"excerpt":{"rendered":" Although small (<2 cm), nonfunctioning pancreatic neuroendocrine tumors (PNETs) are typically followed, there are instances, such as patient anxiety, that prompt resection. Endoscopic ultrasound-guided ethanol ablation (EUS-EA) has been used as an alternative modality to surgery to treat PNETs. This propensity score-matching study aimed to compare the safety and long-term outcomes of EUS-EA with those … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,2052],"tags":[3544,625,3545,3542,3543],"class_list":["post-13527","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-eus","tag-endoscopic-ultrasound-guided-ethanol-ablation","tag-eus","tag-eus-ea","tag-pancreatic-neuroendocrine-tumors","tag-pnets"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13527","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13527"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13527"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13527"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}