Investigators evaluated 30,897 individuals with baseline polypectomy and at least 1 surveillance colonoscopy between 2004 and 2016 across 73 Veterans Administration sites in the U.S., with two-thirds assigned to a training cohort and one-third assigned to a validation cohort. <\/p>\n\n\n\n
In the training set, clinical factors associated with an increased risk of metachronous advanced neoplasia included age (odds ratio [OR], 1.02 per 1-year increase), male gender (OR, 1.99), diabetes (OR, 1.41), current smoker (OR, 1.29), 3 or more adenomas, any adenoma \u226510 mm (OR, 1.54), and villous elements (OR, 1.31). <\/p>\n\n\n\n
Adenoma detection rates (ADRs) were divided into 5 quintiles: quintile 1, ADR \u226419.7%; quintile 2, ADR 19.8% to 32.2%; quintile 3, ADR 32.3% to 39.3%; quintile 4, ADR 39.4% to 47%; and quintile 5, ADR >47%. Compared with quintile 5, quintiles 1, 2, and 3 were all associated with an increased risk of advanced neoplasia, with ORs of 1.48, 1.66, and 1.49, respectively. Quintiles 4 and 5 were not different with regard to the risk. Essentially all of these factors held up in the validation set, except male gender. <\/p>\n\n\n\n
A model based on these factors produced modest improvements in sensitivity and specificity for advanced neoplasia, compared with the 2020 U.S. Multi-Society Task Force on Colorectal Cancer recommendations on postpolypectomy surveillance.<\/p>\n","protected":false},"excerpt":{"rendered":"
Investigators evaluated 30,897 individuals with baseline polypectomy and at least 1 surveillance colonoscopy between 2004 and 2016 across 73 Veterans Administration sites in the U.S., with two-thirds assigned to a training cohort and one-third assigned to a validation cohort. In the training set, clinical factors associated with an increased risk of metachronous advanced neoplasia included … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2470,1933,2058,2139,1814],"class_list":["post-13294","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-adenoma-detection-rate-2","tag-adr-2","tag-colon-2","tag-neoplasia-2","tag-polypectomy-2"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/13294","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=13294"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=13294"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=13294"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}