Benign distal biliary strictures (BBS) are common sequelae of chronic pancreatitis. The usual treatment involves prolonged maximal-caliber stenting, using either serial exchange of multiple plastic stents (MPS) or one or two cycles of large-caliber fully covered self-expanding metal stents (FCSEMS). The authors of this study used a Markov model to estimate the incremental cost-effectiveness ratios of these approaches, assuming MPS exchange every 3 months and FCSEMS remained in place for 6 or 12 months, with 5 years of follow-up and the potential for additional remedial care.<\/p>\n\n\n\n
Treatment with 12 months of FCSEMS, with a cost of $10,938 and effectiveness of 4.58 quality-adjusted life-years (QALYs), was less costly and more effective than therapy with either the shorter indwell time of 6 months ($13,846 and 4.57 QALYs) or serial placement of MPS ($28,587 and 4.53 QALYs). FCSEMS for 12 months remained the most cost-effective option for stricture resolution rates higher than approximately 60%. FCSEMS for 6 months was most cost-effective for resolution rates between 14.75% and 60%. MPS was the preferred strategy in only about 5% of iterations.<\/p>\n","protected":false},"excerpt":{"rendered":"
Benign distal biliary strictures (BBS) are common sequelae of chronic pancreatitis. The usual treatment involves prolonged maximal-caliber stenting, using either serial exchange of multiple plastic stents (MPS) or one or two cycles of large-caliber fully covered self-expanding metal stents (FCSEMS). The authors of this study used a Markov model to estimate the incremental cost-effectiveness ratios … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[3315,3314,2058,2086,3317,3316,3319,3318],"class_list":["post-12304","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-bbs","tag-benign-distal-biliary-strictures","tag-colon-2","tag-fcsems","tag-fully-covered-self-expanding-metal-stents","tag-mps","tag-qalys","tag-quality-adjusted-life-years"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/12304","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=12304"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=12304"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=12304"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}