T2 colorectal cancers (CRCs) are almost invariably treated by surgical resection, but only 25% have lymph node metastases (LNM). An alternative approach in selected cases could be to remove them with the full-thickness resection device, and if the risk of LNM could be predicted as very low, adjuvant surgery might not be warranted.<\/p>\n\n\n\n
This study analyzed 511 consecutive patients with surgical resection of T2 CRC between 2001 and 2016. Four hundred eleven patients were included in the training set for the artificial intelligence (AI) prediction tool and 100 in the validation group. <\/p>\n\n\n\n
The 8 clinical or pathologic features included in the AI algorithm were age, sex, tumor size, tumor location, lymphatic invasion, vascular invasion, tumor differentiation, and serum carcinoembryonic antigen level.<\/p>\n\n\n\n
LNM were present in 26% and 28% of the training and validation sets, respectively. With sensitivity and specificity of 96% and 88%, respectively, set in the algorithm, 64% of patients with T2 CRC could avoid surgery and 1.6% with LNM would not undergo surgery.<\/p>\n","protected":false},"excerpt":{"rendered":"
T2 colorectal cancers (CRCs) are almost invariably treated by surgical resection, but only 25% have lymph node metastases (LNM). An alternative approach in selected cases could be to remove them with the full-thickness resection device, and if the risk of LNM could be predicted as very low, adjuvant surgery might not be warranted. This study … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,2601,2772,2771,3289],"class_list":["post-12238","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-crcs","tag-lnm","tag-lymph-node-metastases","tag-t2-colorectal-cancers"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/12238","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=12238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=12238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=12238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}