{"id":11918,"date":"2022-03-03T17:34:08","date_gmt":"2022-03-03T16:34:08","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=11918"},"modified":"2022-03-03T17:34:09","modified_gmt":"2022-03-03T16:34:09","slug":"impact-of-simethicone-during-bowel-preparation-on-colonoscopy-quality-systematic-review-and-meta-analysis-of-38-randomized-controlled-trials","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/impact-of-simethicone-during-bowel-preparation-on-colonoscopy-quality-systematic-review-and-meta-analysis-of-38-randomized-controlled-trials\/","title":{"rendered":"Impact of Simethicone During Bowel Preparation on Colonoscopy Quality: Systematic Review and Meta-analysis of 38 Randomized Controlled Trials"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Many endoscopists utilize simethicone (SIM) in their bowel preparations for colonoscopy. This systematic review and meta-analysis identified 38 randomized controlled trials relevant to SIM impact on colonoscopy quality. The main findings were:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>SIM increased the rate of Boston Bowel Preparation Scale scores \u22656, the cutoff for adequate bowel preparation, with a risk ratio (RR) of 1.13. All 3 segmental scores improved with SIM, but subgroup analyses indicated that SIM doses should be at least 320 mg.<\/li><li>The adenoma detection rate (ADR) was not different between SIM and non-SIM groups (RR, 1.01), but subgroup analyses indicated an effect for endoscopists with an ADR &lt;31%.<\/li><li>Including SIM in bowel preparation did not impact cecal intubation rates or withdrawal time.<\/li><li>Abdominal distension was reduced by 36% with SIM use, but there was no impact on nausea, vomiting, abdominal pain\/cramps, anal irritation, headache, or sleep disturbance.<\/li><li>Willingness to repeat the same bowel preparation was increased with SIM (RR, 1.15).<\/li><li>There was a clear benefit of SIM in the bowel preparation on foaming and bubbles.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Many endoscopists utilize simethicone (SIM) in their bowel preparations for colonoscopy. This systematic review and meta-analysis identified 38 randomized controlled trials relevant to SIM impact on colonoscopy quality. The main findings were: SIM increased the rate of Boston Bowel Preparation Scale scores \u22656, the cutoff for adequate bowel preparation, with a risk ratio (RR) of &#8230; <a title=\"Impact of Simethicone During Bowel Preparation on Colonoscopy Quality: Systematic Review and Meta-analysis of 38 Randomized Controlled Trials\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/impact-of-simethicone-during-bowel-preparation-on-colonoscopy-quality-systematic-review-and-meta-analysis-of-38-randomized-controlled-trials\/\" aria-label=\"Read more about Impact of Simethicone During Bowel Preparation on Colonoscopy Quality: Systematic Review and Meta-analysis of 38 Randomized Controlled Trials\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,3190,3189],"class_list":["post-11918","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-sim","tag-simethicone"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/11918","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=11918"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=11918"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=11918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}