In a prospective study, 2 experts independently assessed the surfaces of 400 large, laterally spreading colorectal lesions (median size, 35 mm) for predictors of submucosal invasive cancer (SMIC). This predictor was the presence of a demarcated area of vascular disruption. <\/p>\n\n\n\n
Overall sensitivity and specificity of SMIC with high-definition white-light and virtual chromoendoscopy were 73.1% and 92.3%, respectively. As has been previously shown, in flat versus nodular lesions, sensitivity was 90.9% versus 60%, and negative predictive values were 99.5% versus 91.7%, respectively. The experts identified demarcated areas (with the addition of high-definition white-light plus virtual chromoendoscopy) in 51 out of 400 lesions (12.3%). Dye-based chromoendoscopy added nothing to the accuracy of predicting SMIC in either the flat or nodular lesions. The kappa was 0.96 for interobserver agreement between the 2 experts in identifying demarcated areas. There were only 3 cases of discordance between the 2 observers. <\/p>\n","protected":false},"excerpt":{"rendered":"
In a prospective study, 2 experts independently assessed the surfaces of 400 large, laterally spreading colorectal lesions (median size, 35 mm) for predictors of submucosal invasive cancer (SMIC). This predictor was the presence of a demarcated area of vascular disruption. Overall sensitivity and specificity of SMIC with high-definition white-light and virtual chromoendoscopy were 73.1% and … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,3127,3126,2790,2789],"class_list":["post-11544","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-colorectal-lesions","tag-dye-based-chromoendoscopy","tag-smic","tag-submucosal-invasive-cancer"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/11544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=11544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=11544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=11544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}