{"id":10975,"date":"2021-09-21T13:35:07","date_gmt":"2021-09-21T11:35:07","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=10975"},"modified":"2021-09-21T13:35:08","modified_gmt":"2021-09-21T11:35:08","slug":"maternal-obesity-and-pregnancy-weight-gain-and-colorectal-cancer-risk-in-offspring","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/maternal-obesity-and-pregnancy-weight-gain-and-colorectal-cancer-risk-in-offspring\/","title":{"rendered":"Maternal Obesity and Pregnancy Weight Gain and Colorectal Cancer Risk in Offspring"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">This study utilized a database of women and their prenatal care between 1959 and 1966, involving 18,751 live births and 14,507 mothers.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Sixty-eight offspring developed colorectal cancer (CRC) over 738,048 person-years of follow-up, with half diagnosed before age 50 years. The adjusted hazard ratio (aHR) for CRC in offspring was 2.51 with maternal obesity and 2.12 with maternal overweight. Total weight gain during pregnancy was also associated with increased risk. The aHRs for total weight gain at the median of the third and fourth quartiles were 2.09 and 2.54, respectively. Compared with average birth weight (2000 to 3999 g), high birth weight (\u22654000 g; aHR, 1.95) was associated with increased CRC risk.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This study utilized a database of women and their prenatal care between 1959 and 1966, involving 18,751 live births and 14,507 mothers. Sixty-eight offspring developed colorectal cancer (CRC) over 738,048 person-years of follow-up, with half diagnosed before age 50 years. The adjusted hazard ratio (aHR) for CRC in offspring was 2.51 with maternal obesity and &#8230; <a title=\"Maternal Obesity and Pregnancy Weight Gain and Colorectal Cancer Risk in Offspring\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/maternal-obesity-and-pregnancy-weight-gain-and-colorectal-cancer-risk-in-offspring\/\" aria-label=\"Read more about Maternal Obesity and Pregnancy Weight Gain and Colorectal Cancer Risk in Offspring\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,2955,2956],"class_list":["post-10975","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-maternal-obesity","tag-pregnancy-weight-gain"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10975","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10975"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10975"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10975"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}