During endoscopy, the extent of Barrett\u2019s esophagus (BE) is quantified by endoscopists using the widely accepted Prague C&M (circumferential and maximal lengths) criteria. Prague C&M scores can be used to assess the risk of progression but are subjective to endoscopists and their level of experience. <\/p>\n\n\n\n
This single-center pilot study evaluated a novel artificial intelligence (AI)-assisted, automatic, 3-dimensional (3D) system for measuring BE depth and length using the Prague C&M classification system. Initially, an advanced deep learning model was developed by mapping 2-dimensional real-world endoscopy images, which were compared to a 3D phantom esophagus derived from CT and endoscopic images. Measurements of C and M lengths taken during endoscopy were then compared to those of the phantom esophagus ground-truth. The AI system was trained on 10,000 simulated images and validated using 2000 images (20%) for approximately 1000 epochs (100 hours). <\/p>\n\n\n\n
The automatic quantification of the C and M extent had an accuracy of 97.2% (2.8% relative error) and an average deviation of 0.9 mm from the ground-truth measurements. The root mean square error was 1.2 mm, confirming substantial agreement with the ground-truth (Cohen’s kappa [k<\/em>]=0.72 and Spearman correlation [rs<\/em>]= 0.99). C and M measurements made by endoscopists during real-time patient endoscopy in 131 patients were compared to the automated measurement system. <\/p>\n\n\n\n This endoscopy patient cohort comprised 3 subgroups: newly diagnosed BE patients (n=68), BE patients undergoing follow-up without endoscopic therapy (n= 24), and patients with comparison of pre-endoscopic and postendoscopic therapy visits (n= 39). For all patients, the overall relative errors (mean difference) were 8% (3.6 mm) and 7% (2.8 mm) for C and M values, respectively. The highest relative errors were experienced in those patients with BE lengths of 0 to 1 cm. Near-perfect interrater reliability was found between the AI system and endoscopists (k<\/em>=0.84 and rs<\/em>=0.99 for C; k<\/em>=0.87 and rs<\/em>=0.99 for M).<\/p>\n","protected":false},"excerpt":{"rendered":" During endoscopy, the extent of Barrett\u2019s esophagus (BE) is quantified by endoscopists using the widely accepted Prague C&M (circumferential and maximal lengths) criteria. Prague C&M scores can be used to assess the risk of progression but are subjective to endoscopists and their level of experience. This single-center pilot study evaluated a novel artificial intelligence (AI)-assisted, … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1791],"tags":[1944,1929,2098,2950],"class_list":["post-10933","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-esophagus","tag-barretts-esophagus-2","tag-be","tag-esophagus-2","tag-prague-cm"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10933","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10933"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10933"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10933"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}