{"id":10738,"date":"2021-08-06T16:07:19","date_gmt":"2021-08-06T14:07:19","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=10738"},"modified":"2021-08-06T16:07:21","modified_gmt":"2021-08-06T14:07:21","slug":"low-vitamin-d-intake-associated-with-early-onset-colorectal-cancer-in-nurses-health-study","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/low-vitamin-d-intake-associated-with-early-onset-colorectal-cancer-in-nurses-health-study\/","title":{"rendered":"Low Vitamin D Intake Associated With Early Onset Colorectal Cancer in Nurses\u2019 Health Study"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Many investigators are trying to understand the increasing risk of colorectal cancer (CRC) developing before age 50, or so-called early-onset CRC.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Nurses\u2019 Health Study tracks risk factors and health outcomes in mostly female nurses in the U.S. From 1991 to 2015, there were 111 incident cases of early-onset CRC in 1.3 million person-years of follow-up. The hazard ratio (HR) for early-onset CRC was 0.49 for vitamin D intake of \u2265450 IU per day compared to &lt;300 IU per day. The HR was 0.46 for each increase of 400 IU per day. There were also reductions in the diagnosis of conventional adenomas and serrated polyps associated with every increase of 400 IU per day, with odds ratios of 0.76 for adenomas and 0.85 for serrated polyps. Most of the benefit came from vitamin D in dietary sources, with an HR of 0.34 for each increase of 400 IU per day, whereas supplemental vitamin D had an HR of 0.77 that did not reach significance.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Many investigators are trying to understand the increasing risk of colorectal cancer (CRC) developing before age 50, or so-called early-onset CRC.&nbsp; The Nurses\u2019 Health Study tracks risk factors and health outcomes in mostly female nurses in the U.S. From 1991 to 2015, there were 111 incident cases of early-onset CRC in 1.3 million person-years of &#8230; <a title=\"Low Vitamin D Intake Associated With Early Onset Colorectal Cancer in Nurses\u2019 Health Study\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/low-vitamin-d-intake-associated-with-early-onset-colorectal-cancer-in-nurses-health-study\/\" aria-label=\"Read more about Low Vitamin D Intake Associated With Early Onset Colorectal Cancer in Nurses\u2019 Health Study\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,1343,2879,2883,1909],"class_list":["post-10738","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-crc","tag-diet","tag-early-onset-crc","tag-vitamin-d"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10738","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10738"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10738"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10738"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}