A combination of fluoroquinolone (ciprofloxacin, levofloxacin) and metronidazole is the most commonly used antibiotic treatment for outpatient diverticulitis. However, the U.S. Food and Drug Administration has warned that fluoroquinolones are associated with hypoglycemia, aortic dissection, aneurysm, tendon and muscle injury, peripheral neuropathy, and adverse mental health effects. <\/p>\n\n\n\n
The authors evaluated 2 nationwide cohorts for retrospective information on outcomes of fluoroquinolone-metronidazole versus amoxicillin-clavulanate treatment. <\/p>\n\n\n\n
In the 2 cohorts, the use of fluoroquinolone-metronidazole was 8 to 9 times more common than the use of amoxicillin-clavulanate. In both cohorts, the 1-year risk of hospitalization and the 3-year risk of elective surgery were similar between the antibiotic regimens. In the Medicare cohort, there was a higher risk of C difficile<\/em> infection associated with the use of fluoroquinolone-metronidazole (1.2%) than with amoxicillin-clavulanate (0.6%).<\/p>\n","protected":false},"excerpt":{"rendered":" A combination of fluoroquinolone (ciprofloxacin, levofloxacin) and metronidazole is the most commonly used antibiotic treatment for outpatient diverticulitis. However, the U.S. Food and Drug Administration has warned that fluoroquinolones are associated with hypoglycemia, aortic dissection, aneurysm, tendon and muscle injury, peripheral neuropathy, and adverse mental health effects. The authors evaluated 2 nationwide cohorts for retrospective … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2051,2841,2058,2050,2843,2842,2844],"class_list":["post-10636","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-antibiotics","tag-ciprofloxacin","tag-colon-2","tag-diverticulitis","tag-fluoroquinolone","tag-levofloxacin","tag-metronidazole"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}