Before endoscopic resection, large nonpedunculated colorectal lesions should be thoroughly inspected for evidence of submucosal invasive cancer (SMIC). The features to look for are disruption of the normal vascular and pit patterns, often accompanied by a morphologic change such as depression or ulceration. These endoscopic features have often been considered to be specific for SMIC but not sensitive.<\/p>\n\n\n\n
In a new study from the Australian Colonic Endoscopic Resection cohort, the performance of optical evaluation was assessed in 1583 nonpedunculated lesions removed during a 6-year period. The overall sensitivity and specificity for SMIC were 67% and 95%, respectively. For flat compared to nodular lesions, the sensitivity was higher at 91% versus 53%, respectively, and the specificity was similar at 96% versus 94%, respectively. Multivariable predictors of SMIC were size \u226540 mm (odds ratio [OR], 2.0), rectosigmoid location (OR, 2.0), and nodular morphology (OR, 7.2).<\/p>\n","protected":false},"excerpt":{"rendered":"
Before endoscopic resection, large nonpedunculated colorectal lesions should be thoroughly inspected for evidence of submucosal invasive cancer (SMIC). The features to look for are disruption of the normal vascular and pit patterns, often accompanied by a morphologic change such as depression or ulceration. These endoscopic features have often been considered to be specific for SMIC … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[2058,2791,2790,2789],"class_list":["post-10500","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-colon-2","tag-morphology","tag-smic","tag-submucosal-invasive-cancer"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10500","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10500"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10500"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10500"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}