The majority of neoplasia (high-grade dysplasia [HGD] and\/or esophageal adenocarcinoma [EAC]) in patients with Barrett\u2019s esophagus (BE) is detected at the initial endoscopy, ie, prevalent neoplasia. Some studies have reported that up to 19% of all BE neoplasia (HGD or EAC) are detected within 1 year of the initial negative endoscopy, ie, postendoscopy BE neoplasia (PEBN). In this retrospective analysis of a veteran cohort, the authors evaluated the prevalence of dysplasia and neoplasia 3 to 18 months (\u201cmissed\u201d) after an initial diagnosis of nondysplastic BE (NDBE). <\/p>\n\n\n\n
The analysis included 402 patients with NDBE who underwent follow-up endoscopy 3 to 60 months after the initial endoscopy. Of these patients, 271 (67%; 95% males; mean age, 60.8 years) had a follow-up endoscopy 3 to 18 months later and 131 (33%; 95.4% males; mean age, 60.6 years) had follow-up endoscopy 19 to 60 months after the initial endoscopy. Among the patients who had follow-up endoscopy 3 to 18 months later, 38 (14%) progressed to indefinite dysplasia, 9 (3%) to low-grade dysplasia (LGD), 3 (1%) to HGD, and none to EAC. In the patients who had a follow-up endoscopy 19 to 60 months later, 18 (14%) progressed to indefinite dysplasia, 8 (6%) to LGD, 3 (2%) to HGD, and 1 (0.8%) to EAC. A BE length of \u22653 cm was associated with a significantly higher risk of missed dysplasia (odds ratio, 3.39; 95% confidence interval, 1.63-7.08). The authors also noted that the proportion of patients who progressed to definite dysplasia (LGD or HGD) increased significantly over time: 2.7% (3-12 months), 6.7% (13-24 months), 8.6% (25-36 months), and 12.9% (36-60 months) (P<\/em>=.002).<\/p>\n","protected":false},"excerpt":{"rendered":" The majority of neoplasia (high-grade dysplasia [HGD] and\/or esophageal adenocarcinoma [EAC]) in patients with Barrett\u2019s esophagus (BE) is detected at the initial endoscopy, ie, prevalent neoplasia. Some studies have reported that up to 19% of all BE neoplasia (HGD or EAC) are detected within 1 year of the initial negative endoscopy, ie, postendoscopy BE neoplasia … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1791],"tags":[2098,1378,2139,2764,2763],"class_list":["post-10426","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-esophagus","tag-esophagus-2","tag-ndbe","tag-neoplasia-2","tag-pebn","tag-postendoscopy-be-neoplasia"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10426","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10426"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10426"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10426"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}