{"id":10402,"date":"2021-05-13T11:35:25","date_gmt":"2021-05-13T09:35:25","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=10402"},"modified":"2021-05-13T11:35:27","modified_gmt":"2021-05-13T09:35:27","slug":"covered-metal-stents-equal-to-multiple-plastic-stents-for-treatment-of-biliary-strictures-from-chronic-pancreatitis-but-require-fewer-procedures","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/covered-metal-stents-equal-to-multiple-plastic-stents-for-treatment-of-biliary-strictures-from-chronic-pancreatitis-but-require-fewer-procedures\/","title":{"rendered":"Covered Metal Stents Equal to Multiple Plastic Stents for Treatment of Biliary Strictures From Chronic Pancreatitis but Require Fewer Procedures"},"content":{"rendered":"\n<p>Compression of the distal bile duct within a fibrotic pancreas is one complication of chronic pancreatitis (CP), which can lead to chronic cholestasis, cholangitis, and hepatic fibrosis. Endoscopic therapy with prolonged stent placement is indicated for these benign biliary strictures. This prospective, multicenter, randomized study sought to compare outcomes 1 year after 12 months of stent use with 2 or more 8.5 Fr or 10 Fr plastic stents (PS) versus covered self-expanding metal stents (FCSEMS).&nbsp;<\/p>\n\n\n\n<p>Among 80 patients randomized to FCSEMS and 84 to PS, technical success was equivalent (98.6% and 97.6%, respectively). Crossover therapy from PS to FCSEMS was required in 11 patients and from FCSEMS to PS in 10 patients. Twelve months after stent removal, sustained stricture resolution, defined by the absence of need for reintervention and alkaline phosphatase levels remaining less than twice the level at the end of therapy, was observed after FCSEMS in 75.8% of patients (47\/62) and after PS in 77.1% (54\/70) (<em>P<\/em>=.008, noninferiority intention-to-treat [ITT] analysis). The study design yielded more ERCPs for PS (3.9\u00b11.3) than FCSEMS (2.6\u00b11.3) (<em>P<\/em>&lt;.001, ITT). The incidence of serious adverse events was equivalent in both groups (PS, 19% vs FCSEMS, 23.8%;&nbsp;<em>P<\/em>=.568).<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Compression of the distal bile duct within a fibrotic pancreas is one complication of chronic pancreatitis (CP), which can lead to chronic cholestasis, cholangitis, and hepatic fibrosis. Endoscopic therapy with prolonged stent placement is indicated for these benign biliary strictures. This prospective, multicenter, randomized study sought to compare outcomes 1 year after 12 months of &#8230; <a title=\"Covered Metal Stents Equal to Multiple Plastic Stents for Treatment of Biliary Strictures From Chronic Pancreatitis but Require Fewer Procedures\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/covered-metal-stents-equal-to-multiple-plastic-stents-for-treatment-of-biliary-strictures-from-chronic-pancreatitis-but-require-fewer-procedures\/\" aria-label=\"Read more about Covered Metal Stents Equal to Multiple Plastic Stents for Treatment of Biliary Strictures From Chronic Pancreatitis but Require Fewer Procedures\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,67],"tags":[2735,2086,2733,2128,2734,2736],"class_list":["post-10402","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-bauchspeicheldruese-pankreas","tag-biliary-strictures","tag-fcsems","tag-metal-stent","tag-pancreatobiliary","tag-plastic-stent","tag-ps"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10402","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10402"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10402"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10402"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}