{"id":10229,"date":"2021-03-29T12:47:09","date_gmt":"2021-03-29T10:47:09","guid":{"rendered":"https:\/\/www.endoscopy-campus.com\/?post_type=ec-news&#038;p=10229"},"modified":"2021-03-29T12:47:10","modified_gmt":"2021-03-29T10:47:10","slug":"selective-serotonin-reuptake-inhibitors-reduce-colorectal-cancer-risk-and-the-effect-is-additive-to-aspirin","status":"publish","type":"ec-news","link":"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/selective-serotonin-reuptake-inhibitors-reduce-colorectal-cancer-risk-and-the-effect-is-additive-to-aspirin\/","title":{"rendered":"Selective Serotonin Reuptake Inhibitors Reduce Colorectal Cancer Risk, and the Effect Is Additive to Aspirin"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">In a nationwide Swedish registry study, 24,786 colorectal cancer (CRC) cases and 74,358 randomly matched controls for birth year and sex were evaluated to determine whether monotherapy or combined selective serotonin reuptake inhibitor (SSRI) and aspirin use reduce CRC risk.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Aspirin monotherapy was associated with a 9% reduction in CRC risk, and SSRI use was associated with a 7% reduction. Evaluation of combined aspirin and SSRI users showed that combined therapy produced a 23% reduction in CRC risk, and the effects were additive, not synergistic.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Of 5 individual SSRIs evaluated, the clearest benefits occurred with sertraline and citalopram.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In a nationwide Swedish registry study, 24,786 colorectal cancer (CRC) cases and 74,358 randomly matched controls for birth year and sex were evaluated to determine whether monotherapy or combined selective serotonin reuptake inhibitor (SSRI) and aspirin use reduce CRC risk.&nbsp; Aspirin monotherapy was associated with a 9% reduction in CRC risk, and SSRI use was &#8230; <a title=\"Selective Serotonin Reuptake Inhibitors Reduce Colorectal Cancer Risk, and the Effect Is Additive to Aspirin\" class=\"read-more\" href=\"https:\/\/www.endoscopy-campus.com\/en\/ec-news\/selective-serotonin-reuptake-inhibitors-reduce-colorectal-cancer-risk-and-the-effect-is-additive-to-aspirin\/\" aria-label=\"Read more about Selective Serotonin Reuptake Inhibitors Reduce Colorectal Cancer Risk, and the Effect Is Additive to Aspirin\">Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1769],"tags":[1712,2058,1343,2701],"class_list":["post-10229","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-asge-kolon","tag-aspirin-2","tag-colon-2","tag-crc","tag-ssri"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10229","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10229"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10229"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10229"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}