Buried Barrett\u2019s esophagus (BE) mucosa, or subsquamous intestinal metaplasia, is defined as intestinal metaplasia that is present under a lining of endoscopically intact squamous epithelium. It has been reported in up to 28% of treatment-na\u00efve patients with BE and 14% of patients after endoscopic therapy for BE. However, this diagnosis poses challenges: Were biopsy samples obtained from the squamous mucosa or endoscopically appearing columnar areas such as islands or tongues? Several experts have proposed that due to a lack of clear endoscopic features, specimens obtained for biopsy are truly random, which might contribute to this erroneous diagnosis of buried BE. <\/p>\n\n\n\n
The authors of this study arrived at a consensus on 2 endoscopic features of buried BE: (1) squamous epithelium, which appears darker pink with white-light endoscopy (WLE) or darker brown with narrow-band imaging (NBI), and (2) a slightly raised or nodular appearance of the mucosa. These findings were evaluated in a single-center retrospective review of 506 patients with dysplastic BE, both treatment-na\u00efve and treated with postendoscopic therapy. Overall, 33 patients (7%) had histological evidence of buried BE, with 26 of these patients (79%) showing endoscopic suspicion of buried BE using the criteria mentioned. Twenty-four percent of the patients had darker pink (WLE) or darker brown (NBI) squamous epithelium, 27% had slightly raised or nodular mucosal appearance, and 27% had both features. Of the 12 patients with dysplasia in buried BE, 92% had positive endoscopic features. The pretest characteristics suggested that the sensitivity, specificity, and positive-predictive value of identifying buried BE using these endoscopic criteria were 79%, 31%, and 59%, respectively.<\/p>\n","protected":false},"excerpt":{"rendered":"
Buried Barrett\u2019s esophagus (BE) mucosa, or subsquamous intestinal metaplasia, is defined as intestinal metaplasia that is present under a lining of endoscopically intact squamous epithelium. It has been reported in up to 28% of treatment-na\u00efve patients with BE and 14% of patients after endoscopic therapy for BE. However, this diagnosis poses challenges: Were biopsy samples … Read more<\/a><\/p>\n","protected":false},"template":"","categories":[1768,1791],"tags":[1929,2646,2098,2647,280,2648,2649],"class_list":["post-10027","ec-news","type-ec-news","status-publish","hentry","category-asge-journal-scan","category-esophagus","tag-be","tag-buried-barretts-esophagus","tag-esophagus-2","tag-narrow-band-imaging-2","tag-nbi","tag-white-light-endoscopy","tag-wle"],"_links":{"self":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news\/10027","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/ec-news"}],"about":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/types\/ec-news"}],"wp:attachment":[{"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/media?parent=10027"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/categories?post=10027"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.endoscopy-campus.com\/en\/wp-json\/wp\/v2\/tags?post=10027"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}